Denver Broncos vs Buffalo Bills Odds, Spread & Prediction Monday Night Football Week 10

Buffalo Bills quarterback Josh Allen (17) hands off to running back James Cook (4) in the second quarter of the NFL Week 9 game between the Cincinnati Bengals and the Buffalo Bills at Paycor Stadium in Cincinnati on Sunday, Nov. 5, 2023.The Buffalo Bills are 7-point home favorites over the Denver Broncos in the NFL Week 10 MNF game on Monday, November 13Buffalo is 7-0 against the spread in the last seven games against DenverThe Broncos are 2-7 straight up in their last nine prime-time games

When assessing the data for the NFL Week 10 MNF game that sees the Denver Broncos (3-5, 2-5-1 ATS) on the road facing the Buffalo Bills (5-4, 3-6 ATS), all of the metrics are pointing toward one conclusion – a Bills victory, and mostly likely, a resounding one.

Straight up, the Broncos are 2-7 in their last nine appearances in prime-time NFL games. That includes a 19-8 loss to the Kansas City Chiefs earlier this season on TNF.

Secondly, the Bills are 7-0 against the spread in the last seven games facing the Broncos. Denver hasn’t won at Buffalo since a 15-14 win in 2007. The Broncos haven’t covered at Buffalo since a 28-17 win in 2005.

Oddsmakers are anticipating more of the same. It’s hometown Buffalo that is set as the 7-point chalk in in the Broncos vs Bills odds. Buffalo is 2-2 ATS as the home chalk this season.

Broncos vs Bills Odds

In the Denver vs Buffalo odds, the Bills are -340 moneyline favorites, giving them a 77.27% implied win probability. The total is set at 47.5 points. The total is 2-2 in Buffalo home games this season.

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Odds as of November 12 at FanDuel Sportsbook.

Kickoff for this game at Highmark Stadium on Monday, November 13, is set for 8:15pm ET. The broadcast is being carried by ABC and ESPN, as well as by DAZN in Canada. ESPN has announced an agreement with PENN Entertainment to launch a new sportsbook branded as ESPN BET. Set to launch on November 14, bettors can check out the latest news on the upcoming ESPN Bet promo code.

Denver vs Buffalo Betting Trends

The Broncos have won just three times at Buffalo since 1990. Denver is 1-6 ATS in the team’s last seven visits to Buffalo. In the NFL public betting splits, the people are anticipating that Buffalo will be continuing this trend. The Bills are getting 59% of spread bets and 96% of moneyline bets.

Buffalo, though is 0-5 ATS over the club’s past five games. The Bills are also 2-6 ATS in the last eight meetings with an AFC West opponent. But they are 16-3 SU in their last 19 home games.

The total has gone over in nine of Denver’s last 13 games. Five of Buffalo’s past six clashes with AFC West teams were also producing an over outcome.

Buffalo is the co-eighth betting choice in the Super Bowl odds at +1500. Denver is set with 6.5 as the club’s number in the NFL win totals. Bet it either way and the odds are -110.

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Bills Have Been Downright Offensive

Earlier in the week in preparation for this game, the members of the Bills offense called a players-only meeting to air their grievances. Since a resounding 48-20 thumping of the Miami Dolphins on Oct. 1, Buffalo’s vaunted offensive unit has struggled, making their stars tough over plays in the Week 10 NFL player props.

Trent Sherfield explaining the atmosphere in the locker room that led to today's players only offensive meeting:

"It's not because the building was burning down… it's because we know the talent we have in that room."#Bills pic.twitter.com/Ng0q9wZdJZ

— Thad Brown (@thadbrown7) November 9, 2023

The Bills have produced a combined total of 101 points over their past five games, going over 20 points just three times in that span, but never higher than 25 points. During that time frame, they are 2-3 SU.

Broncos On Hot Streak

Coming into this game off a bye week, Denver is riding a two-game win streak after starting the season 1-5 SU. The Broncos whipped the Kansas City Chiefs 24-9 at home in Week 8.

Final prep for #DENvsBUF. ✅

📸 » https://t.co/jlDl838Bgj pic.twitter.com/dlR3hd6jNd

— Denver Broncos (@Broncos) November 11, 2023

However, on the road, Denver is 1-7 SU and 2-5-1 ATS over the past eight games. Even the extra days to prepare might not make all that much difference. Since 2020, the Broncos are 5-4 ATS with a rest advantage. The Bills are 6-5 ATS with a rest disadvantage over the same span of time.

Broncos vs Bills Prediction

Denver is just 2-7 SU in the club’s past nine prime-time games. All-time, the Broncos are 30-35-1 (.462) SU on MNF. They’ve lost their last six MNF road games. Buffalo, though, is only 17-24 (.415) SU on MNF.

Denver has scored as many as 20 points just once in the past five games against Buffalo. The Broncos haven’t counted 20 points in a game at Buffalo since that aforementioned 28-17 victory in 2005. That was five visits ago.

That being said, Denver is playing with momentum right now, while Buffalo is stumbling. Take the Broncos and the points.

Broncos vs Bills Picks: Denver Broncos +7 (-115)

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